* Each launcher can store 8 missiles, which are launched more rapidly than new ones can be produced (once every 2.3 seconds for each launcher). The Volley Attack launches missiles every .2 seconds until the reserves are depleted. The missiles have a max velocity of 1,250 m/s, can accelerate at 1,650 m/s^2, and each have 120 hit points.

The guided missile has long been a forgotten weapon in space combat. Small cheap missiles lacked the warhead strength and range to be a factor, while missiles large enough to be a threat simply could not be carried in large enough numbers on even capital ships to make it worth the time and resources. Kushan Engineers finally made a tactical breakthrough by applying the automated construction bay technologies used in the Mothership and, to a lesser extent, in Imperator Class Carriers. Missile Destroyers use the standard Destroyer hull, but replace the Ion Cannon systems with an automated assembly bay, capable of building a heavy missile armed with a fusion warhead every 5 seconds. A dual rail missile launcher is mounted on either side of the forward hull where the standards weapon bays used to be.

Missile Destroyers have the best stand-off range of any ship in the fleet, but are vulnerable once their initial load of 32 missiles has been launched, and their rate of fire drops to how fast they can manufacture new missiles.

The Missile Destroyer is the supreme anti-fighter platform in Homeworld. Two destroyers can more or less decimate almost any fighter attack.